2013 Philip S. Portoghese Medicinal Chemistry Lectureship: Drug Discovery Targeting Allosteric Sites-Reference-Cited by-同舟云学术

2013 Philip S. Portoghese Medicinal Chemistry Lectureship: Drug Discovery Targeting Allosteric Sites

Published:2014-09-15 Issue:18 Volume:57 Page:7485-7498
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lindsley Craig W.¹

Affiliation:

1. Departments of Pharmacology and Chemistry, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt Specialized Chemistry Center (MLPCN), Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States

Funder

National Institutes of Health

National Institute of Mental Health

National Institute on Drug Abuse

Bristol-Myers Squibb

AstraZeneca

Seaside Therapeutics

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5011786

Reference91 articles.

1. Lindsley, C. W.Adventures in allosteric drug discovery. Presented at the 246th National Meeting of the American Chemical Society, Indianapolis, IN, September 10, 2013; The 2013 Portoghese Lectureship.

2. Seven Transmembrane Receptors as Shapeshifting Proteins: The Impact of Allosteric Modulation and Functional Selectivity on New Drug Discovery

3. Allostery: an illustrated definition for the ‘second secret of life’

4. Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

5. G-Protein-Coupled Receptors: From Classical Modes of Modulation to Allosteric Mechanisms

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