Naturally Occurring Homoisoflavonoids Function as Potent Protein Tyrosine Kinase Inhibitors by c-Src-Based High-Throughput Screening-Reference-Cited by-同舟云学术

Naturally Occurring Homoisoflavonoids Function as Potent Protein Tyrosine Kinase Inhibitors by c-Src-Based High-Throughput Screening

Published:2008-07-09 Issue:15 Volume:51 Page:4419-4429
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lin Li-Gen¹,Xie Hua¹,Li Hong-Lin¹,Tong Lin-Jiang¹,Tang Chun-Ping¹,Ke Chang-Qiang¹,Liu Qun-Fang¹,Lin Li-Ping¹,Geng Mei-Yu¹,Jiang Hualiang¹,Zhao Wei-Min¹,Ding Jian¹,Ye Yang¹

Affiliation:

1. Department of Natural Products Chemistry, Division of Anti-tumor Pharmacology and Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People’s Republic of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701501x

Reference32 articles.

1. Tyrosine kinase inhibitors: From rational design to clinical trials

2. Targeting Tyrosine Kinases in Cancer: The Second Wave

3. Establishment of the active catalytic domain of human PDGFRβ tyrosine kinase-based ELISA assay for inhibitor screening

4. Role of Src expression and activation in human cancer

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