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Tyrosine kinase inhibitors: From rational design to clinical trials

Published:2001 Issue:6 Volume:21 Page:499-512
ISSN:0198-6325
Container-title:Medicinal Research Reviews
language:en
Short-container-title:Med. Res. Rev.

Author:

Traxler Peter,Bold Guido,Buchdunger Elisabeth,Caravatti Giorgio,Furet Pascal,Manley Paul,O'Reilly Terence,Wood Jeanette,Zimmermann Juerg

Publisher

Wiley

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Reference53 articles.

1. Modelling study of protein kinase inhibitors: Binding mode of staurosporine and origin of the selectivity of CGP 52411

2. Development of a Binding Model to Protein Tyrosine Kinases for Substituted Pyrido[2,3-d]pyrimidine Inhibitors

3. Use of a Pharmacophore Model for the Design of EGFR Tyrosine Kinase Inhibitors: Isoflavones and 3-Phenyl-4(1H)-quinolones

4. Tyrosine kinase inhibitors in cancer treatment (Part II)

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