NMR-Based Metabonomic Studies on the Biochemical Effects of Commonly Used Drug Carrier Vehicles in the Rat-Reference-Cited by-同舟云学术

NMR-Based Metabonomic Studies on the Biochemical Effects of Commonly Used Drug Carrier Vehicles in the Rat

Published:2002-08-09 Issue:9 Volume:15 Page:1136-1141
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Beckwith-Hall Bridgette M.¹,Holmes Elaine¹,Lindon John C.¹,Gounarides John¹,Vickers Alison¹,Shapiro Michael¹,Nicholson Jeremy K.¹

Affiliation:

1. Biological Chemistry, Biomedical Sciences Division, Imperial College of Science, Technology and Medicine, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, U.K., Novartis Pharmaceuticals Corporation, Core Technologies, 556 Morris Avenue, Summit, New Jersey 07901-1398

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx020020%2B

Reference26 articles.

1. Metabonomics: a platform for studying drug toxicity and gene function

2. Holmes, E., Bonner, F. W., Sweatman, B. C., Lindon, J. C., Beddell, C. R., Rahr, E., and Nicholson, J. K. (1992) Nuclear magnetic resonance spectroscopy and pattern recognition investigations into the biochemical processes associated with the progression and recovery from nephrotoxic lesions in the rat induced by mercury II chloride and 2-bromoethanamine.Mol. Pharmacol.42, 922−930.

Cited by 58 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pharmacokinetics of 40 kDa PEG in rodents using high-field NMR spectroscopy;Journal of Pharmaceutical and Biomedical Analysis;2019-07

2. Metabolic markers for differentiation between renal allograft rejection and immunosuppressant toxicity in rat urine;Metabolomics;2017-07-28

3. APPENDIX E: COMMON VEHICLES FOR THE NONCLINICAL EVALUATION OF THERAPEUTIC AGENTS;Drug Safety Evaluation;2017-01-03

4. NMR-based metabonomic analysis of normal rat urine and faeces in response to (±)-venlafaxine treatment;Journal of Pharmaceutical and Biomedical Analysis;2016-05

5. Tolerable Levels of Nonclinical Vehicles and Formulations Used in Studies by Multiple Routes in Multiple Species With Notes on Methods to Improve Utility;International Journal of Toxicology;2016-01-10