A Series of α-Amino Acid Ester Prodrugs of Camptothecin: In Vitro Hydrolysis and A549 Human Lung Carcinoma Cell Cytotoxicity
Author:
Affiliation:
1. Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854
2. UMDNJ-Rutgers CounterACT Research Center of Excellence, Piscataway, New Jersey 08854
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm901029n
Reference59 articles.
1. Studies on camptothecin-induced degradation and apparent reaggregation of DNA from L1210 cells
2. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex
3. XMT-1001, a novel polymeric camptothecin pro-drug in clinical development for patients with advanced cancer
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