Synthesis and biological activity assay of novel camptothecin-peptidic conjugates based on PEPT1

Author:

Zhang Qiang,Zou Ping,Zhu Meixuan,Sui Dan,Wang Shaoming,Hu Zhiwei,Wang Yang,Jing Lijia,Zheng JianORCID

Funder

Fundamental Research Funds for the Central Universities

Postdoctoral Scientific Research Development Fund of Heilongjiang Province

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

1. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2;Wall;J Am Chem Soc,1966

2. Treatment of malignant melanoma with camptothecin (NSC-100880);Gottlieb;Cancer Chemother Rep,1972

3. Phase II study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer;Moertel;Cancer Chemother Rep,1972

4. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I;Hsiang;J Biol Chem,1985

5. A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues;Fassberg;J Pharm Sci,1992

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