On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex
Author:
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi00437a018
Reference52 articles.
1. Selective Interruption of High Molecular Weight RNA Synthesis in HeLa Cells by Camptothecin
2. Prodrug analogs of the antitumor alkaloid camptothecin
3. Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.
4. Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks.
5. Evidence for an intermediate with a single-strand break in the reaction catalyzed by the DNA untwisting enzyme.
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