A General Method for the Synthesis of 2‘-O-Cyanoethylated Oligoribonucleotides Having Promising Hybridization Affinity for DNA and RNA and Enhanced Nuclease Resistance-Reference-Cited by-同舟云学术

A General Method for the Synthesis of 2‘-O-Cyanoethylated Oligoribonucleotides Having Promising Hybridization Affinity for DNA and RNA and Enhanced Nuclease Resistance

Published:2005-11-10 Issue:25 Volume:70 Page:10453-10460
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Saneyoshi Hisao¹,Seio Kohji¹,Sekine Mitsuo¹

Affiliation:

1. Department of Life Science, Tokyo Institute of Technology, Division of Collaborative Research for Bioscience and Biotechnology, Frontier Collaborative Research Center, and CREST, JST (Japan Science and Technology Agency), Nagatsuta, Midoriku, Yokohama 226-8501, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo051741r

Reference59 articles.

1. Antisense technologies. Improvement through novel chemical modifications

2. Recent improvements in antigene technology

3. RNA interference and chemically modified small interfering RNAs

4. siRNA and miRNA: an insight into RISCs

5. siRNAs: applications in functional genomics and potential as therapeutics

Cited by 82 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A Visual Compendium of Principal Modifications within the Nucleic Acid Sugar Phosphate Backbone;Molecules;2024-06-26

2. A Convenient Method for the Synthesis of 2′‐O‐Cyanoethylated Nucleotides and Their Application in the Solid‐Phase Synthesis of Related RNA Analogs;Current Protocols;2023-11

3. Synthesis of 2′-O-[3-(N-methylsulfamoyl)propan-1-yl]ribothymidine as a potentially applicable 2′-modified nucleoside for antisense oligonucleotides;Bioorganic & Medicinal Chemistry;2022-11

4. Influence of Sugar Modifications on the Nucleoside Conformation and Oligonucleotide Stability: A Critical Review;The Chemical Record;2022-09

5. Generation of oligonucleotide conjugates via one-pot diselenide-selenoester ligation–deselenization/alkylation;Chemical Science;2022