Generation of oligonucleotide conjugates via one-pot diselenide-selenoester ligation–deselenization/alkylation-Reference-Cited by-同舟云学术

Generation of oligonucleotide conjugates via one-pot diselenide-selenoester ligation–deselenization/alkylation

Published:2022 Issue:2 Volume:13 Page:410-420
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Liczner Christopher¹^ORCID,Hanna Cameron C.²³^ORCID,Payne Richard J.²³^ORCID,Wilds Christopher J.¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, Concordia University, 7141 Rue Sherbrooke Ouest, Montréal, Québec, H4B 1R6, Canada

2. School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia

3. Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, Sydney, NSW 2006, Australia

Abstract

An efficient and versatile approach for the late-stage generation of oligonucleotide conjugates by diselenide-selenoester ligation (DSL)–deselenization/alkylation was developed.

Funder

Natural Sciences and Engineering Research Council of Canada

Fonds de recherche du Québec – Nature et technologies

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D1SC04937B

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