Ring Closing Metathesis Mediated Synthesis of 4a-Aryloxodecahydroisoquinolines, Intermediates in the Preparation of Novel Opiates
Author:
Affiliation:
1. Pfizer Global Research and Development, Groton, Connecticut 06340
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol016588b
Reference16 articles.
1. Discovery of a Novel Class of Substituted Pyrrolooctahydroisoquinolines as Potent and Selective δ Opioid Agonists, Based on an Extension of the Message−Address Concept
2. Synthesis of 4a-aryldecahydroisoquinolines. Functionality in the carbocyclic ring
3. An efficient synthesis of the 4a-aryl-6-oxodecahydroisoquinolines
4. Synthesis, antinociceptive activity and opioid receptor profiles of substituted trans-3-(decahydro- and octahydro-4a-isoquinolinyl)phenols
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