Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain-Reference-Cited by-同舟云学术

Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain

Published:2015-04-07 Issue:15 Volume:54 Page:2481-2489
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Chen Jhong-Min¹,Hou Caixia¹,Wang Guojun¹,Tsodikov Oleg V.¹,Rohr Jürgen¹

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky 40536-0596, United States

Funder

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi501462g

Reference35 articles.

1. The aureolic acid family of antitumor compounds: structure, mode of action, biosynthesis, and novel derivatives

2. UCH9, a New Antitumor Antibiotic Produced byStreptomyces. II. Structure Elucidation of UCH9 by Mass and NMR Spectroscopy.

3. Durhamycin A, a Potent Inhibitor of HIV Tat Transactivation

4. Differential Interactions of the Mg2+ Complexes of Chromomycin A3 and Mithramycin with Poly(dG-dC)·Poly(dC-dG) and Poly(dG)·Poly(dC)

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