Durhamycin A, a Potent Inhibitor of HIV Tat Transactivation
Author:
Affiliation:
1. Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, West Point, Pennsylvania 19486, and Merck Sharp & Dohme de Espana S. A. Josefa Valcarcel 38, 28027 Madrid, Spain
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/np010642f
Reference12 articles.
1. TAR-independent activation of the HIV-1 LTR: Evidence that Tat requires specific regions of the promoter
2. The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation.
3. HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation
4. HIV TAR: An RNA enhancer?
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