Discovery and Structure−Activity Relationships of Novel Piperidine Inhibitors of Farnesyltransferase-Reference-Cited by-同舟云学术

Discovery and Structure−Activity Relationships of Novel Piperidine Inhibitors of Farnesyltransferase

Published:2003-05-02 Issue:12 Volume:46 Page:2467-2473
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nara Shinji¹,Tanaka Rieko¹,Eishima Jun¹,Hara Mitsunobu¹,Takahashi Yuichi¹,Otaki Shizuo¹,Foglesong Robert J.¹,Hughes Philip F.¹,Turkington Shelley¹,Kanda Yutaka¹

Affiliation:

1. Pharmaceutical Research Institute, Kyowa Hakko Kogyo Co., Ltd., 1188 Shimotogari, Nagaizumi-cho, Shizuoka 411-8731, Japan, and Sphinx Laboratories, A Division of Eli Lilly and Co., Research Triangle Park, North Carolina 27709

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020522k

Reference15 articles.

1. New approaches to anticancer drug design based on the inhibition of farnesyltransferase

2. Ras Protein Farnesyltransferase: A Strategic Target for Anticancer Therapeutic Development

3. Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

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