Conformationally Constrained Nicotines: Polycyclic, Bridged, and Spiro-Annulated Analogues as Novel Ligands for the Nicotinic Acetylcholine Receptor-Reference-Cited by-同舟云学术

Conformationally Constrained Nicotines: Polycyclic, Bridged, and Spiro-Annulated Analogues as Novel Ligands for the Nicotinic Acetylcholine Receptor

Published:2002-08-01 Issue:18 Volume:45 Page:4047-4054
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ullrich Thomas¹,Krich Sylvia¹,Binder Dieter¹,Mereiter Kurt¹,Anderson David J.¹,Meyer Michael D.¹,Pyerin Michael¹

Affiliation:

1. Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9/E163, A-1060 Vienna, Austria, Institute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/E164, A-1060 Vienna, Austria, and Neurological and Urological Diseases Research, Pharmaceutical Products Division, Abbott Laboratories, Department 47W, Building AP-9A/311, 100 Abbott Park Road, Abbott Park, Illinois 60064-6125

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020916b

Reference26 articles.

1. The identification of novel structural compound classes exhibiting high affinity for neuronal nicotinic acetylcholine receptors and analgesic efficacy in preclinical models of pain

2. Nicotinic acetylcholine involvement in cognitive function in animals

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