Base mediated spirocyclization of quinazoline: one-step synthesis of spiro-isoindolinone dihydroquinazolinones-Reference-Cited by-同舟云学术

Base mediated spirocyclization of quinazoline: one-step synthesis of spiro-isoindolinone dihydroquinazolinones

Published:2020 Issue:16 Volume:10 Page:9486-9491
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Venkateshwarlu Rapolu¹²³⁴⁵,Murthy V. Narayana¹²³⁴⁵,Tadiparthi Krishnaji⁶⁷⁸⁵,Nikumbh Satish P.¹²³⁴⁵,Jinkala Rajesh¹²³⁴⁵,Siddaiah Vidavalur⁹¹⁰¹¹⁵,Madhu babu M. V.¹²³⁴⁵,Rama Mohan Hindupur¹²³⁴⁵,Raghunadh Akula¹²³⁴⁵^ORCID

Affiliation:

1. Technology Development Centre

2. Custom Pharmaceutical Services

3. Dr. Reddy's Laboratories Ltd.

4. Hyderabad 500049

5. India

6. Department of Chemistry

7. CHRIST (Deemed to be University)

8. Bengaluru 560029

9. Department of Organic Chemistry and FDW

10. Andhra University

11. Visakhapatnam 530045

Abstract

A novel approach for the spiro-isoindolinone dihydroquinazolinones has been demonstrated from 2-aminobenzamide and 2-cyanomethyl benzoate in the presence of KHMDS as a base to get moderate yields.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/C9RA09567E

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