Targeting Matrix Metalloproteinases: Exploring the Dynamics of the S1′ Pocket in the Design of Selective, Small Molecule Inhibitors
Author:
Affiliation:
1. Departamento de Química y Bioquímica, Facultad de Farmacia, Universidad CEU San Pablo, Urbanización Monteprincipe, 28668 Madrid, Spain
Funder
Ministerio de Economía y Competitividad
Fundación Universitaria San Pablo CEU
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm500505f
Reference115 articles.
1. Matrix metalloproteinases: a tail of a frog that became a prince
2. Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations
3. Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
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5. MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover
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