Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis-Reference-Cited by-同舟云学术

Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis

Published:2023-10-20 Issue:21 Volume:66 Page:14653-14668
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Abe-Sato Kumi¹^ORCID,Tabuse Hideaki¹^ORCID,Kanazawa Harumi¹,Kamitani Masafumi²,Endo Mayumi²,Tokura Seiken²,Wakabayashi Satoshi³,Yahara Tohru³^ORCID,Takeda Takuya⁴,Hitaka Kosuke⁴,Gunji Emi⁴,Kojima Naoki⁴,Oka Yusuke¹^ORCID

Affiliation:

1. Medicinal Chemistry Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403, Yoshino-Cho, Kita-Ku, Saitama, Saitama 331-9530, Japan

2. Discovery Technologies Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403, Yoshino-Cho, Kita-Ku, Saitama, Saitama 331-9530, Japan

3. Drug Metabolism and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403, Yoshino-Cho, Kita-Ku, Saitama, Saitama 331-9530, Japan

4. Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403, Yoshino-Cho, Kita-Ku, Saitama, Saitama 331-9530, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01166

Reference49 articles.

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2. Matrix metalloproteinases: they're not just for matrix anymore!

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5. Biological role of matrix metalloproteinases: a critical balance

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