Accelerating Pharmaceutical Process Development with an Acoustic Droplet Ejection-Multiple Reaction Monitoring-Mass Spectrometry Workflow-Reference-Cited by-同舟云学术

Accelerating Pharmaceutical Process Development with an Acoustic Droplet Ejection-Multiple Reaction Monitoring-Mass Spectrometry Workflow

Published:2024-01-02 Issue:3 Volume:96 Page:1138-1146
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Hu Hang¹^ORCID,Singh Andrew N.¹,Lehnherr Dan²^ORCID,Mdluli Velabo²^ORCID,Chun Stephanie W.²^ORCID,Makarewicz Amanda M.²,Gouker Joseph R.²,Ukaegbu Ophelia¹,Li Shasha¹,Wen Xiujuan³^ORCID,McLaren David G.³,Velasquez Juan E.²,Moore Jeffrey C.²^ORCID,Galanie Stephanie²^ORCID,Appiah-Amponsah Emmanuel¹,Regalado Erik L.¹^ORCID

Affiliation:

1. Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States

2. Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States

3. Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey 07065, United States

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c04211

Reference54 articles.

1. The importance of synthetic chemistry in the pharmaceutical industry

2. Engineering biosynthetic enzymes for industrial natural product synthesis

3. A Perspective on the Analytical Challenges Encountered in High-Throughput Experimentation

4. The Emergence of Universal Chromatographic Methods in the Research and Development of New Drug Substances

5. Trapping‐Enrichment Multi‐dimensional Liquid Chromatography with On‐Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram Scale

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