Engineering biosynthetic enzymes for industrial natural product synthesis-Reference-Cited by-同舟云学术

Engineering biosynthetic enzymes for industrial natural product synthesis

Published:2020 Issue:8 Volume:37 Page:1122-1143
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Galanie Stephanie¹²³⁴^ORCID,Entwistle David⁵⁶⁷⁴^ORCID,Lalonde James⁸⁹¹⁰⁴

Affiliation:

1. Biosciences Division

2. Oak Ridge National Laboratory

3. Oak Ridge

4. USA

5. Process Chemistry

6. Codexis, Inc.

7. Redwood City

8. Microbial Digital Genome Engineering

9. Inscripta, Inc.

10. Pleasanton

Abstract

This review describes examples of the broadening industrial relevance of engineered secondary metabolism enzymes, natural products and analogs being made with these enzymes, and technology improvements that have enabled their development since 1999.

Funder

Oak Ridge National Laboratory

Biological and Environmental Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NP/C9NP00071B

Reference230 articles.

1. Industrial biocatalysis today and tomorrow

2. Directed evolution of industrial enzymes

3. Engineering the third wave of biocatalysis

4. Methods for the directed evolution of proteins

5. Directed Evolution of Protein Catalysts

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