First Steps toward Uncovering Gene Doping with CRISPR/Cas by Identifying SpCas9 in Plasma via HPLC

First Steps toward Uncovering Gene Doping with CRISPR/Cas by Identifying SpCas9 in Plasma via HPLC–HRMS/MS

Published:2020-11-25 Issue:24 Volume:92 Page:16322-16328
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Paßreiter Alina¹,Thomas Andreas¹,Grogna Nicolas²,Delahaut Philippe²,Thevis Mario¹^ORCID

Affiliation:

1. Center for Preventive Doping Research/Institute of Biochemistry, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany

2. CER Groupe—Département Santé, Rue du Point du Jour 8, 6900 Marloie, Belgium

Funder

Deutsche Sporthochschule K?ln

Manfred-Donike Institute for Doping Analysis

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.0c04445

Reference35 articles.

1. The new frontier of genome engineering with CRISPR-Cas9

2. Expanding the Biologist’s Toolkit with CRISPR-Cas9

3. Multiplex Genome Engineering Using CRISPR/Cas Systems

4. Heritable Gene Knockout in Caenorhabditis elegans by Direct Injection of Cas9–sgRNA Ribonucleoproteins

5. Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells

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