Detection of sgRNA via SHERLOCK as Potential CRISPR Related Gene Doping Control Strategy

Author:

Paßreiter Alina1,Naumann Nana1,Thomas Andreas1,Grogna Nicolas2,Delahaut Philippe2,Thevis Mario13ORCID

Affiliation:

1. Center for Preventive Doping Research/Institute of Biochemistry, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany

2. CER Groupe − Département Santé, Rue du Point du Jour 8, 6900 Marche-en-Famenne, Belgium

3. European Monitoring Center for Emerging Doping Agents (EuMoCEDA), Am Sportpark Müngersdorf 6, 50933 Cologne, Germany

Funder

World Anti-Doping Agency

Deutsche Sporthochschule K?ln

Manfred Donike Institut f?r Dopinganalytik

Publisher

American Chemical Society (ACS)

Reference33 articles.

1. Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

2. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

3. Genome engineering using the CRISPR-Cas9 system

4. Vertex and CRISPR Therapeutics Announce Authorization of the First CRISPR/Cas9 Gene-Edited Therapy, CASGEVY (exagamglogene autotemcel), by the United Kingdom MHRA for the Treatment of Sickle Cell Disease and Transfusion-Dependent Beta Thalassemia. Vertex News & Events, 2023. https://investors.vrtx.com/news-releases/news-release-details/vertex-and-crispr-therapeutics-announce-authorization-first.

5. A brief history of the development of a gene doping test

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