Conformational Preference of Macrocycles Investigated by Ion-Mobility Mass Spectrometry and Distance Geometry Modeling
Author:
Affiliation:
1. Department of Chemistry, University of Tennessee, Knoxville, Tennessee 37996, United States
2. Department of Chemistry, Zhejiang University, Hangzhou 310027, China
Funder
University of Tennessee
Agilent Technologies
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.9b02100
Reference75 articles.
1. Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery
2. The exploration of macrocycles for drug discovery — an underexploited structural class
3. Macrocycles: lessons from the distant past, recent developments, and future directions
4. How Beyond Rule of 5 Drugs and Clinical Candidates Bind to Their Targets
5. Quantifying the chameleonic properties of macrocycles and other high-molecular-weight drugs
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