Quantifying the chameleonic properties of macrocycles and other high-molecular-weight drugs
Author:
Funder
NIH
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology
Reference28 articles.
1. The impact of natural products upon modern drug discovery;Ganesan;Curr. Opin. Chem. Biol.,2008
2. Oral druggable space beyond the Rule of 5: insights from drugs and clinical candidates;Doak;Chem. Biol.,2014
3. The exploration of macrocycles for drug discovery – an underexploited structural class;Driggers;Nat. Rev. Drug Discov.,2008
4. How proteins bind macrocycles;Villar;Nat. Chem. Biol.,2014
5. Macrocyclic drugs and clinical candidates: what can medicinal chemists learn from their properties?;Giordanetto;J. Med. Chem.,2014
Cited by 197 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Computational methods and key considerations for in silico design of proteolysis targeting chimera (PROTACs);International Journal of Biological Macromolecules;2024-10
2. Solid-Phase Synthesis of Diverse Macrocycles by Regiospecific 2-Pyridone Formation: Scope and Applications;JACS Au;2024-08-12
3. CREMP: Conformer-rotamer ensembles of macrocyclic peptides for machine learning;Scientific Data;2024-08-09
4. MuCoCP: a priori chemical knowledge-based multimodal contrastive learning pre-trained neural network for the prediction of cyclic peptide membrane penetration ability;Bioinformatics;2024-07-27
5. CycPeptMP: enhancing membrane permeability prediction of cyclic peptides with multi-level molecular features and data augmentation;Briefings in Bioinformatics;2024-07-25
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3