Synthesis and Biological Evaluation of Novel Bisbenzimidazoles as Escherichia coli Topoisomerase IA Inhibitors and Potential Antibacterial Agents-Reference-Cited by-同舟云学术

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Synthesis and Biological Evaluation of Novel Bisbenzimidazoles as Escherichia coli Topoisomerase IA Inhibitors and Potential Antibacterial Agents

Published:2014-06-04 Issue:12 Volume:57 Page:5238-5257
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nimesh Hemlata¹,Sur Souvik¹,Sinha Devapriya¹,Yadav Pooja¹,Anand Prachi²,Bajaj Priyanka³,Virdi Jugsharan S.³,Tandon Vibha¹⁴

Affiliation:

1. Department of Chemistry, University of Delhi, Delhi 110 007, India

2. Department of Chemistry & Biochemistry, CUNY−Hunter College, New York, New York 10065, United States

3. Department of Microbiology, University of Delhi, Delhi 110 021, India

4. Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110 067, India

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5003028

Reference64 articles.

1. Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced pKa: Antibacterial Agents with an Improved Safety Profile

2. Novel target sites in bacteria for overcoming antibiotic resistance

3. Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I

4. A Model for the Mechanism of Human Topoisomerase I

5. DNA Topoisomerases: Structure, Function, and Mechanism

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