Synthesis of 4-Substituted Chlorophthalazines, Dihydrobenzoazepinediones, 2-Pyrazolylbenzoic Acid, and 2-Pyrazolylbenzohydrazide via 3-Substituted 3-Hydroxyisoindolin-1-ones-Reference-Cited by-同舟云学术

Synthesis of 4-Substituted Chlorophthalazines, Dihydrobenzoazepinediones, 2-Pyrazolylbenzoic Acid, and 2-Pyrazolylbenzohydrazide via 3-Substituted 3-Hydroxyisoindolin-1-ones

Published:2012-04-05 Issue:8 Volume:77 Page:3887-3906
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Nguyen Hanh Nho,Cee Victor J.¹,Deak Holly L.,Du Bingfan,Faber Kathleen Panter,Gunaydin Hakan,Hodous Brian L.,Hollis Steven L.,Krolikowski Paul H.,Olivieri Philip R.,Patel Vinod F.,Romero Karina,Schenkel Laurie B.,Geuns-Meyer Stephanie D.

Affiliation:

1. Department of Medicinal Chemistry, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo3000628

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4. Metabolism and Disposition of Vatalanib (PTK787/ZK-222584) in Cancer Patients

5. Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines

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