Ecological Niche-Inspired Genome Mining Leads to the Discovery of Crop-Protecting Nonribosomal Lipopeptides Featuring a Transient Amino Acid Building Block

Author:

Götze Sebastian1ORCID,Vij Raghav2,Burow Katja3,Thome Nicola1ORCID,Urbat Lennart1,Schlosser Nicolas4ORCID,Pflanze Sebastian1ORCID,Müller Rita2,Hänsch Veit G.5ORCID,Schlabach Kevin1,Fazlikhani Leila3,Walther Grit6,Dahse Hans-Martin7,Regestein Lars4ORCID,Brunke Sascha2,Hube Bernhard2,Hertweck Christian5ORCID,Franken Philipp38,Stallforth Pierre19ORCID

Affiliation:

1. Department of Paleobiotechnology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Beutenbergstraße 11a, 07745 Jena, Germany

2. Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Beutenbergstraße 11a, 07745 Jena, Germany

3. Research Centre for Horticultural Crops (FGK), Fachhochschule Erfurt, Kühnhäuser Straße 101, 99090 Erfurt, Germany

4. Bio Pilot Plant, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Beutenbergstraße 11a, 07745 Jena, Germany

5. Department of Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Beutenbergstraße 11a, 07745 Jena, Germany

6. National Reference Center for Invasive Fungal Infections, Hans Knöll Institute, Beutenbergstraße 11a, 07745 Jena, Germany

7. Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Beutenbergstraße 11a, 07745 Jena, Germany

8. Molecular Phytopathology, Friedrich Schiller University, 07745 Jena, Germany

9. Faculty of Chemistry and Earth Sciences, Institute of Organic Chemistry and Macromolecular Chemistry, Friedrich Schiller University Jena, Humboldtstraße 10, 07743 Jena, Germany

Funder

Leibniz-Gemeinschaft

Werner Siemens-Stiftung

Deutsche Forschungsgemeinschaft

Bundesministerium f??r Bildung, Wissenschaft und Forschung

Dr. Illing Stiftung

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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