Nonribosomal peptides protect Pseudomonas nunensis 4A2e from amoebal and nematodal predation

Author:

Pflanze Sebastian1ORCID,Mukherji Ruchira1,Ibrahim Anan1ORCID,Günther Markus1,Götze Sebastian1ORCID,Chowdhury Somak1,Reimer Lisa1,Regestein Lars2,Stallforth Pierre13ORCID

Affiliation:

1. Department of Paleobiotechnology, Leibniz Institute for Natural Product Research and Infection Biology – Leibniz-HKI, Beutenbergstrasse 11a, 07745 Jena, Germany

2. Bio Pilot Plant, Leibniz Institute for Natural Product Research and Infection Biology – Leibniz-HKI, Beutenbergstrasse 11a, 07745 Jena, Germany

3. Faculty of Chemistry and Earth Sciences, Friedrich Schiller University (FSU), Jena, Germany

Abstract

Genome mining of the environmental bacterial isolate Pseudomonas nunensis 4A2e led to the discovery of three novel lipopeptides. Ecology-inspired bioassays highlight their importance in protecting the producing organism against various predators.

Funder

Deutsche Forschungsgemeinschaft

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie – Hans-Knöll-Institut

Werner Siemens-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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