Nonribosomal peptides protect <i>Pseudomonas nunensis</i> 4A2e from amoebal and nematodal predation-Reference-Cited by-同舟云学术

Nonribosomal peptides protect Pseudomonas nunensis 4A2e from amoebal and nematodal predation

Published:2023 Issue:41 Volume:14 Page:11573-11581
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Pflanze Sebastian¹^ORCID,Mukherji Ruchira¹,Ibrahim Anan¹^ORCID,Günther Markus¹,Götze Sebastian¹^ORCID,Chowdhury Somak¹,Reimer Lisa¹,Regestein Lars²,Stallforth Pierre¹³^ORCID

Affiliation:

1. Department of Paleobiotechnology, Leibniz Institute for Natural Product Research and Infection Biology – Leibniz-HKI, Beutenbergstrasse 11a, 07745 Jena, Germany

2. Bio Pilot Plant, Leibniz Institute for Natural Product Research and Infection Biology – Leibniz-HKI, Beutenbergstrasse 11a, 07745 Jena, Germany

3. Faculty of Chemistry and Earth Sciences, Friedrich Schiller University (FSU), Jena, Germany

Abstract

Genome mining of the environmental bacterial isolate Pseudomonas nunensis 4A2e led to the discovery of three novel lipopeptides. Ecology-inspired bioassays highlight their importance in protecting the producing organism against various predators.

Funder

Deutsche Forschungsgemeinschaft

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie – Hans-Knöll-Institut

Werner Siemens-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC03335J

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1. Bacterial predator-prey coevolution accelerates genome evolution and selects on virulence-associated prey defences