Process Development and Large-Scale Synthesis of a c-Met Kinase Inhibitor-Reference-Cited by-同舟云学术

Process Development and Large-Scale Synthesis of a c-Met Kinase Inhibitor

Published:2010-06-02 Issue:4 Volume:14 Page:849-858
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Stewart Gavin W.¹,Brands Karel M. J.¹,Brewer Sarah E.¹,Cowden Cameron J.¹,Davies Antony J.¹,Edwards John S.¹,Gibson Andrew W.¹,Hamilton Simon E.¹,Katz Jason D.¹,Keen Stephen P.¹,Mullens Peter R.¹,Scott Jeremy P.¹,Wallace Debra J.¹,Wise Christopher S.¹

Affiliation:

1. Department of Process Research, Merck Sharp and Dohme Research Laboratories, Hertford Road, Hoddesdon, Hertfordshire, EN11 9BU, U.K., and Department of Chemistry, Merck and Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, U.S.A.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op100101q

Reference14 articles.

1. Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition

2. Receptor Tyrosine Kinases as Therapeutic Targets the Model of the MET Oncogene

3. Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network

4. Acquisition of Invasive Phenotype in Gallbladder Cancer Cells via Mutual Interaction of Stromal Fibroblasts and Cancer Cells as Mediated by Hepatocyte Growth Factor

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Palladium Extraction Following Metal-Catalyzed Reactions: Recent Advances and Applications in the Pharmaceutical Industry;Organic Process Research & Development;2023-09-06

2. Synthesis of 2,2-Disubstituted and 2,2,3-Trisubstituted 1,4-Dioxane-Derived Building Blocks;Synthesis;2023-05-12

3. Übergangsmetallkatalysierte Kupplungsreaktionen;Organische Synthesemethoden;2023

4. From Milligram to Kilogram Manufacture of AZD4573: Making It Possible by Application of Enzyme-, Iridium-, and Palladium-Catalyzed Key Transformations;Organic Process Research & Development;2021-07-21

5. Kilogram-Scale Preparation of an Aminopyrazole Building Block via Copper-Catalyzed Aryl Amidation;Organic Process Research & Development;2021-04-06