Polyalkoxybenzenes from Plants. 5. Parsley Seed Extract in Synthesis of Azapodophyllotoxins Featuring Strong Tubulin Destabilizing Activity in the Sea Urchin Embryo and Cell Culture Assays-Reference-Cited by-同舟云学术

Polyalkoxybenzenes from Plants. 5. Parsley Seed Extract in Synthesis of Azapodophyllotoxins Featuring Strong Tubulin Destabilizing Activity in the Sea Urchin Embryo and Cell Culture Assays

Published:2011-09-29 Issue:20 Volume:54 Page:7138-7149
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Semenova Marina N.¹²,Kiselyov Alex S.³,Tsyganov Dmitry V.⁴,Konyushkin Leonid D.⁴,Firgang Sergei I.⁴,Semenov Roman V.⁴,Malyshev Oleg R.⁴,Raihstat Mikhail M.⁴,Fuchs Fabian⁵,Stielow Anne⁵,Lantow Margareta⁵⁶,Philchenkov Alex A.⁷,Zavelevich Michael P.⁷,Zefirov Nikolay S.⁸,Kuznetsov Sergei A.⁵,Semenov Victor V.²⁴

Affiliation:

1. Institute of Developmental Biology, RAS, 26 Vavilov Street, 119334 Moscow, Russian Federation

2. Chemical Block Ltd., 3 Kyriacou Matsi, 3723 Limassol, Cyprus

3. CHDI Foundation, 6080 Center Drive, Suite 100, Los Angeles California 90045, United States

4. N. D. Zelinsky Institute of Organic Chemistry, RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation

5. Institute of Biological Sciences, University of Rostock, 3 Albert-Einstein-Strasse, D-18059 Rostock, Germany

6. Department of Pathology, Immunology and Laboratory Medicine, University of Florida, 1600 Archer Road, Gainesville Florida 32610, United States

7. R. E. Kavetsky Institute of Experimental Oncology, Pathology, and Radiobiology, National Academy of Sciences of Ukraine, 45 Vasyl′kivska Street, 03022 Kyiv, Ukraine

8. Lomonosov Moscow State University, GSP-1, Leninskie Gory, 119991 Moscow, Russian Federation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200737s

Reference74 articles.

1. Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain

2. Oxalone and Lactone Moieties of Podophyllotoxin Exhibit Properties of Both the B and C Rings of Colchicine in Its Binding with Tubulin

3. Synthesis and anti-HIV-1 activities of novel podophyllotoxin derivatives

4. Podophyllotoxin directly binds a hinge domain in E2 of HPV and inhibits an E2/E7 interaction in vitro

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