Different Hepatic Concentrations of Bromobenzene, 1,2-Dibromobenzene, and 1,4-Dibromobenzene in Humanized-Liver Mice Predicted Using Simplified Physiologically Based Pharmacokinetic Models as Putative Markers of Toxicological Potential
Author:
Affiliation:
1. Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan
2. Laboratory Animal Research Department, Central Institute for Experimental Animals, Kawasaki-ku, Kawasaki 210-0821, Japan
Funder
Ministry of Economy, Trade and Industry
Japan Society for the Promotion of Science
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.0c00387
Reference21 articles.
1. Simultaneous analysis of 28 urinary VOC metabolites using ultra high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UPLC-ESI/MSMS)
2. Using Biologic Markers in Blood to Assess Exposure to Multiple Environmental Chemicals for Inner-City Children 3–6 Years of Age
3. The contribution of bromobenzene to our current understanding of chemically-induced toxicities
4. Potential tolerance against bromobenzene-induced acute hepatotoxicity due to prior subchronic exposure
5. Changes in Selected Indicators of Liver Impairment after Repeated Administration of Mono- and Polybromobenzenes in Mice
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