Forward and reverse dosimetry for aniline and 2,6-dimethylaniline in humans extrapolated from humanized-liver mouse data using simplified physiologically based pharmacokinetic models
Author:
Affiliation:
1. Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University
2. Laboratory Animal Research Department, Central Institute for Experimental Animals
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/47/12/47_531/_pdf
Reference29 articles.
1. Bugosen, S., Mantilla, I.D. and Tarazona-Vasquez, F. (2020): Techno-economic analysis of aniline production via amination of phenol. Heliyon, 6, e05778.
2. Chinthakindi, S. and Kannan, K. (2021): Primary aromatic amines in indoor dust from 10 countries and associated human exposure. Environ. Int., 157, 106840.
3. Chinthakindi, S. and Kannan, K. (2022a): Urinary and fecal excretion of aromatic amines in pet dogs and cats from the United States. Environ. Int., 163, 107208.
4. Chinthakindi, S. and Kannan, K. (2022b): Variability in urinary concentrations of primary aromatic amines. Sci. Total Environ., 831, 154768.
5. Gonçalves, L.L., Beland, F.A. and Marques, M.M. (2001): Synthesis, characterization, and comparative 32P-postlabeling efficiencies of 2,6-dimethylaniline-DNA adducts. Chem. Res. Toxicol., 14, 165-174.
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