Differences in Toxicological and Pharmacological Responses Mediated by Polymorphic Cytochromes P450 and Related Drug-Metabolizing Enzymes-Reference-Cited by-同舟云学术

Differences in Toxicological and Pharmacological Responses Mediated by Polymorphic Cytochromes P450 and Related Drug-Metabolizing Enzymes

Published:2016-10-26 Issue:1 Volume:30 Page:53-60
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Yamazaki Hiroshi¹

Affiliation:

1. Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo 194-8543, Japan

Funder

Ministry of Education, Culture, Sports, Science, and Technology

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.6b00286

Reference71 articles.

1. Individual Differences in Toxicological Response Caused by a Diversity of Chemicals: Observations in Japan

2. Combination of GSH Trapping and Time-Dependent Inhibition Assays as a Predictive Method of Drugs Generating Highly Reactive Metabolites

3. Identification of Novel Liver-Specific mRNAs in Plasma for Biomarkers of Drug-Induced Liver Injury and Quantitative Evaluation in Rats Treated With Various Hepatotoxic Compounds

4. Albumin and apolipoprotein H mRNAs in human plasma as potential clinical biomarkers of liver injury: analyses of plasma liver-specific mRNAs in patients with liver injury

5. Contributions of Human Enzymes in Carcinogen Metabolism

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