An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms-Reference-Cited by-同舟云学术

An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms

Published:2017-01-13 Issue:2 Volume:12 Page:564-573
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Arencibia Jose M.¹,Fröhner Wolfgang²,Krupa Magdalena¹,Pastor-Flores Daniel¹,Merker Piotr¹,Oellerich Thomas³,Neimanis Sonja¹,Schmithals Christian¹,Köberle Verena¹,Süß Evelyn¹,Zeuzem Stefan¹,Stark Holger⁴,Piiper Albrecht¹,Odadzic Dalibor⁴,Schulze Jörg O.¹,Biondi Ricardo M.¹⁵^ORCID

Affiliation:

1. Research Group PhosphoSites, Medizinische Klinik 1, Universitätsklinikum Frankfurt, 60590 Frankfurt am Main, Germany

2. Pharmaceutical and Medicinal Chemistry, Saarland University, Saarbrücken, Germany

3. Department of Hematology/Oncology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany

4. Institut für Pharmazeutische Chemie, Johann Wolfgang Goethe Universität, Frankfurt am Main, Germany

5. German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany

Funder

Bundesministerium für Bildung und Forschung

Deutsche Forschungsgemeinschaft

Hessisches Ministerium für Wissenschaft und Kunst

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.6b00827

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