Insilico design of an allosteric modulator targeting the protein–protein interaction site of 3 Phosphoinositide dependent Kinase-1: design, synthesis and biological activity
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s40203-023-00160-6.pdf
Reference33 articles.
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4. Bai LY, Chiu CF, Kapuriya NP, Shieh TM, Tsai YC, Wu CY et al (2015) BX795, a TBK1 inhibitor, exhibits antitumor activity in human oral squamous cell carcinoma through apoptosis induction and mitotic phase arrest. Eur J Pharmacol [internet] 769:287–296
5. Beekman AM, Cominetti MMD, Walpole SJ, Prabhu S, O’Connell MA, Angulo J et al (2019) Identification of selective protein-protein interaction inhibitors using efficient: in silico peptide-directed ligand design. Chem Sci 10(16):4502–4508
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