Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism-Reference-Cited by-同舟云学术

Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism

Published:2016-07-19 Issue:9 Volume:11 Page:2529-2540
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Ahn Kay¹²,Boehm Markus¹²,Brown Matthew F.¹²,Calloway Jessica¹²,Che Ye¹²,Chen Jinshan¹²,Fennell Kimberly F.¹²,Geoghegan Kieran F.¹²,Gilbert Adam M.¹²,Gutierrez Jemy A.¹²,Kalgutkar Amit S.¹²,Lanba Adhiraj¹²,Limberakis Chris¹²,Magee Thomas V.¹²,O’Doherty Inish¹²,Oliver Robert¹²,Pabst Brandon¹²,Pandit Jayvardhan¹²,Parris Kevin¹²,Pfefferkorn Jeffrey A.¹²,Rolph Timothy P.¹²,Patel Rushi¹²,Schuff Brandon¹²,Shanmugasundaram Veerabahu¹²,Starr Jeremy T.¹²,Varghese Alison H.¹²,Vera Nicholas B.¹²,Vernochet Cecile¹²,Yan Jiangli¹²

Affiliation:

1. Cardiovascular, Metabolic, and Endocrine Diseases (CVMED) Research Unit, Pfizer Inc., 610 Main Street, Cambridge, Massachusetts 02139, United States

2. Worldwide Medicinal Chemistry and §Pharmacokinetics, Dynamics, & Metabolism, Pfizer Inc., Eastern Point Road, Groton, Connecticut 06340, United States

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.6b00266

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