(2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes
Author:
Affiliation:
1. Merck Research Laboratories, Merck & Co., Inc., Rahway, New Jersey 07065
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0493156
Reference47 articles.
1. Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study
2. Truncated GLP-1 (proglucagon 78?107-amide) inhibits gastric and pancreatic functions in man
3. Genistein potentiates wild-type and delta F508-CFTR channel activity
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