Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue
Author:
Affiliation:
1. Medicine Design, Pfizer Inc., Eastern Point Road, Groton, Connecticut 06340, United States
2. Medicine Design, Pfizer Inc., 610 Main Street, Cambridge, Massachusetts 02139, United States
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.7b00403
Reference29 articles.
1. Developing Irreversible Inhibitors of the Protein Kinase Cysteinome
2. Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes
3. Decapping Scavenger (DcpS) enzyme: Advances in its structure, activity and roles in the cap-dependent mRNA metabolism
4. The human decapping scavenger enzyme DcpS modulates microRNA turnover
5. DcpS as a Therapeutic Target for Spinal Muscular Atrophy
Cited by 93 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Recent advances in photochemical and electrochemical strategies for the synthesis of sulfonyl fluorides;Organic Chemistry Frontiers;2024
2. Covalent hits and where to find them;SLAS Discovery;2024-01
3. Synthesis and structure–activity relationships of aryl fluorosulfate-based inhibitors as novel antitubercular agents;Bioorganic & Medicinal Chemistry Letters;2024-01
4. Offsetting Low-Affinity Carbohydrate Binding with Covalency to Engage Sugar-Specific Proteins for Tumor-Immune Proximity Induction;ACS Central Science;2023-11-03
5. Covalent fragment approaches targeting non-cysteine residues;Trends in Pharmacological Sciences;2023-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3