Relationship of the Topological Distances and Activities between mPGES-1 and COX-2 versus COX-1: Implications of the Different Post-Translational Endoplasmic Reticulum Organizations of COX-1 and COX-2
Author:
Affiliation:
1. Department of Pharmacological and Pharmaceutical Sciences, Center for Experimental Therapeutics and Pharmacoinformatics, College of Pharmacy, University of Houston, Houston, Texas 77204-5037, United States
Funder
National Heart, Lung, and Blood Institute
American Heart Association
U.S. Army
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.5b00339
Reference15 articles.
1. Prostaglandins and Inflammation
2. PGI2as a Regulator of Inflammatory Diseases
3. Prostaglandin E synthase
4. Roles of Cyclooxygenase (COX)-1 and COX-2 in Prostanoid Production by Human Endothelial Cells: Selective Up-Regulation of Prostacyclin Synthesis by COX-2
5. Microsomal prostaglandin E synthase-1, which is not coupled to a particular cyclooxygenase isoenzyme, is essential for prostaglandin E2biosynthesis in vascular smooth muscle cells
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