Reversing thromboxane A2 receptor activity from calcium to cAMP signaling by shifting Gαq to Gαs covalently linked to the receptor-Reference-Cited by-同舟云学术

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Reversing thromboxane A2 receptor activity from calcium to cAMP signaling by shifting Gαq to Gαs covalently linked to the receptor

Published:2022-06 Issue: Volume:184 Page:108465
ISSN:1369-703X
Container-title:Biochemical Engineering Journal
language:en
Short-container-title:Biochemical Engineering Journal

Author:

Li Qun-Ying,Li Yan,Inoue Asuka,Lu Renzhong,Xu Anna,Ruan Ke-He

Funder

American Heart Association

National Institutes of Health

Publisher

Elsevier BV

Subject

Biomedical Engineering,Environmental Engineering,Bioengineering,Biotechnology

Reference43 articles.

1. Establishing novel prostacyclin-synthesizing cells with therapeutic potential against heart diseases;Ruan;Int. J. Cardiol.,2013

2. Engineering of a novel hybrid enzyme: an anti-inflammatory drug target with triple catalytic activities directly converting arachidonic acid into the inflammatory prostaglandin E(2);Ruan;Protein Eng. Des. Sel.,2009

3. Characterization of the prostaglandin H(2) mimic: binding to the purified human thromboxane A(2) receptor in solution;Ruan;Arch. Biochem. Biophys.,2008

4. An active triple‐catalytic hybrid enzyme engineered by linking cyclo‐oxygenase isoform‐1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector;Ruan;FEBS J.,2008

5. Prostacyclin therapy for pulmonary arterial hypertension;Ruan;Tex. Heart Inst. J.,2010

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Reprogramming Megakaryocytes for Controlled Release of Platelet-like Particles Carrying a Single-Chain Thromboxane A2 Receptor-G-Protein Complex with Therapeutic Potential;Cells;2023-12-06

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