Synthesis, in vitro and in silico studies on novel 3-aryloxymethyl-5-[(2-oxo-2-arylethyl)sulfanyl]-1,2,4-triazoles and their oxime derivatives as potent inhibitors of mPGES-1-Reference-Cited by-同舟云学术

Synthesis, in vitro and in silico studies on novel 3-aryloxymethyl-5-[(2-oxo-2-arylethyl)sulfanyl]-1,2,4-triazoles and their oxime derivatives as potent inhibitors of mPGES-1

Published:2023-01 Issue: Volume:1272 Page:134154
ISSN:0022-2860
Container-title:Journal of Molecular Structure
language:en
Short-container-title:Journal of Molecular Structure

Author:

Erensoy Gizem,Ding Kai,Zhan Chang-Guo,Çiftçi Gamze,Yelekçi Kemal,Duracık Merve,Bingöl Özakpınar Özlem,Aydemir Esra,Yılmaz Zübeyde Nur,Şahin Fikrettin,Kulabaş Necla^ORCID,Tatar Esra,Küçükgüzel İlkay^ORCID

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference86 articles.

1. Lipid Mediators in Life Science;Murakami;Exp. Anim.,2011

2. Membrane prostaglandin E synthase-1: a novel therapeutic target;Samuelsson;Pharmacol. Rev.,2007

3. Relationship of the Topological Distances and Activities between mPGES-1 and COX-2 versus COX-1: implications of the Different Post-Translational Endoplasmic Reticulum Organizations of COX-1 and COX-2;Akasaka;Biochemistry,2015

4. P.-.J. Jakobsson, S. Thoren, R. Morgenstern, B. Samuelsson, Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target, Proc. Natl. Acad. Sci. 96 (1999) 7220–7225. https://doi.org/10.1073/pnas.96.13.7220.

5. Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease;Wang;J. Intern. Med.,2008

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Novel azole-urea hybrids as VEGFR-2 inhibitors: Synthesis, in vitro antiproliferative evaluation and in silico studies;Journal of Molecular Structure;2023-12

2. Recent developments in the chemistry of 1H- and 4H-1,2,4-triazoles;Advances in Heterocyclic Chemistry;2023

3. In silico investigation of novel 5-benzylidene-2- (arylsulfonylhydrazono)thiazolidine-4-ones as potential inhibitors of mPGES-1 and COX-2.;Journal of Research in Pharmacy;2023