P450-Catalyzed Tailoring Steps in Leinamycin Biosynthesis Featuring Regio- and Stereoselective Hydroxylations and Substrate Promiscuities
Author:
Funder
National Cancer Institute
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.8b00623
Reference37 articles.
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2. Leinamycin, a new antitumor antibiotic from Streptomyces; Producing organism, fermentation and isolation.
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5. Synthesis and evaluation of 8,4′-dideshydroxy-leinamycin revealing new insights into the structure–activity relationship of the anticancer natural product leinamycin
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