Molecular Dynamics Simulations of the Hypoxia-Inducible Factor PAS-B Domain Confirm That Internally Bound Water Molecules Function To Stabilize the Protein Core for Ligand Binding-Reference-Cited by-同舟云学术

Molecular Dynamics Simulations of the Hypoxia-Inducible Factor PAS-B Domain Confirm That Internally Bound Water Molecules Function To Stabilize the Protein Core for Ligand Binding

Published:2019-12-23 Issue:4 Volume:59 Page:450-459
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Chong Andrew S.¹,Anderson Peter C.¹^ORCID

Affiliation:

1. Department of Physical Sciences, University of Washington Bothell, Bothell, Washington 98011, United States

Funder

University of Washington Bothell

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.9b00872

Reference47 articles.

1. Dominant forces in protein folding

2. The hydrophobic effect in protein folding

3. PROTEIN FOLDING: The Endgame

4. Forces stabilizing proteins

5. Computational Repacking of HIF-2α Cavity Replaces Water-Based Stabilized Core

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