Evaluation of Several Routes to Advanced Pregabalin Intermediates: Synthesis and Enantioselective Enzymatic Reduction Using Ene-Reductases
Author:
Affiliation:
1. Pfizer Global Process Development Centre, Loughbeg, County Cork, Ireland
2. Pfizer Chemical R&D, Eastern Point Road, Groton, Connecticut 06340, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op4002774
Reference46 articles.
1. Pregabalin: a new anxiolytic
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3. An Enantioselective Synthesis of (S)-(+)-3-Aminomethyl-5-methylhexanoic Acid via Asymmetric Hydrogenation
4. Highly Selective Asymmetric Hydrogenation Using a Three Hindered Quadrant Bisphosphine Rhodium Catalyst
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