1. Dowpharma, Chirotech Technology Limited, A Subsidiary of The Dow Chemical Company, Cambridge Science Park, Milton Road, Cambridge CB4 0WG, United Kingdom, Pfizer Global Research and Development, Pfizer Inc., 188 Howard Avenue, Holland, Michigan 49424, and Pfizer Global Research and Development, Pfizer Inc., 2800 Plymouth Road, Ann Arbor, Michigan 48105 jramsden@dow.com