<i>In Vitro</i> Antimicrobial Evaluation, Single-Point Resistance Study, and Radiosterilization of Novel Pyrazole Incorporating Thiazol-4-one/Thiophene Derivatives as Dual DNA Gyrase and DHFR Inhibitors against MDR Pathogens-Reference-Cited by-同舟云学术

In Vitro Antimicrobial Evaluation, Single-Point Resistance Study, and Radiosterilization of Novel Pyrazole Incorporating Thiazol-4-one/Thiophene Derivatives as Dual DNA Gyrase and DHFR Inhibitors against MDR Pathogens

Published:2022-02-03 Issue:6 Volume:7 Page:4970-4990
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Ali Mohamed Hazem¹,Ammar Yousry A.¹,A.M. Elhagali Gameel¹,A. Eyada Hassan¹,S. Aboul-Magd Dina²,Ragab Ahmed¹^ORCID

Affiliation:

1. Chemistry Department, Faculty of Science (Boys), Al-Azhar University, Nasr City, Cairo 11884, Egypt

2. Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.1c05801

Reference72 articles.

1. Microorganisms Causing Community-Acquired Acute Bronchitis: The Role of Bacterial Infection

2. Exploiting a Bacterial Drug-Resistance Mechanism: A Light-Activated Construct for the Destruction of MRSA

3. Drugs for bad bugs: confronting the challenges of antibacterial discovery

4. One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor

5. Administration, U. S. F. and D. Drugs@ FDA: FDA Approved Drug Products; US Food and Drug Administration: Rockville, MD, 2011.

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