Synthesis of 1-Azaspiro[4.4]nonane Derivatives Enabled by Domino Radical Bicyclization Involving Formation and Capture of Alkoxyaminyl Radicals

Author:

Guerrero-Caicedo Alejandro1,Soto-Martínez Diana M.1,Osorio David A.1,Novoa Muskendol1,Loaiza Alix E.2,Jaramillo-Gómez Luz M.1ORCID

Affiliation:

1. Department of Chemistry, Universidad del Valle, Calle 13 # 100-00, Cali 760032, Colombia

2. Department of Chemistry, Pontificia Universidad Javeriana, Cra 7 No 40-62, Edificio Carlos Ortiz 52, Bogotá D. C. 110231561, Colombia

Funder

Departamento Administrativo de Ciencia, Tecnolog?a e Innovaci?n

Universidad del Valle

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Reference44 articles.

1. Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects

2. d Zhang, Y.; Zhang, J.; Xie, H.; Ren, Q.; Wu, X.; Luo, H.; Fu, C.; Hu, B.; Li, S.; Tang, C.; Lei, Y.; Yu, Q.; Fang, Q.; Qang, C. Spiro ring compounds as hepatitis C virus (HCV) inhibitors. PCT Int. Appl. WO 2014048072A120140403, 2014 [CAN 160:530540].

3. Conformationally Constrained Nicotines:  Polycyclic, Bridged, and Spiro-Annulated Analogues as Novel Ligands for the Nicotinic Acetylcholine Receptor

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