Synthesis and Structure−Activity Relationships of Phenylenebis(methylene)- Linked Bis-tetraazamacrocycles That Inhibit Human Immunodeficiency Virus Replication. 2. Effect of Heteroaromatic Linkers on the Activity of Bicyclams-Reference-Cited by-同舟云学术

Synthesis and Structure−Activity Relationships of Phenylenebis(methylene)- Linked Bis-tetraazamacrocycles That Inhibit Human Immunodeficiency Virus Replication. 2. Effect of Heteroaromatic Linkers on the Activity of Bicyclams

Published:1996-01-01 Issue:1 Volume:39 Page:109-119
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bridger Gary J.¹,Skerlj Renato T.¹,Padmanabhan Sreenivasan¹,Martellucci Stephen A.¹,Henson Geoffrey W.¹,Abrams Michael J.¹,Joao Heidi C.¹,Witvrouw Myriam¹,De Vreese Karen¹,Pauwels Rudi¹,De Clercq Erik¹

Affiliation:

1. Johnson Matthey Pharmaceutical Research, 1401 King Road, West Chester, Pennsylvania 19380, Sandoz Research Institute, Brunner Strasse 59, A-1235 Vienna, Austria, and Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm950584t

Reference44 articles.

1. Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event.

2. Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100

3. Synthesis and Structure-Activity Relationships of Phenylenebis(methylene)-Linked Bis-Tetraazamacrocycles That Inhibit HIV Replication. Effects of Macrocyclic Ring Size and Substituents on the Aromatic Linker

4. Preparation of lanthanide tellurolates and evidence for the formation of cluster intermediates in their thermal decomposition to bulk metal tellurides

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