Design, synthesis, and biological characterization of a new class of symmetrical polyamine-based small molecule CXCR4 antagonists-Reference-Cited by-同舟云学术

Design, synthesis, and biological characterization of a new class of symmetrical polyamine-based small molecule CXCR4 antagonists

Published:2020-08 Issue: Volume:200 Page:112410
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Fang Xiong,Meng Qian,Zhang Huijun,Liang Boqiang,Zhu Siyu,Wang Juan,Zhang Chaozai,Huang Lina S.,Zhang Xingquan,Schooley Robert T.,An Jing,Xu Yan,Huang Ziwei

Funder

Tsinghua-Peking Joint Center for Life Sciences

Tsinghua University

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference52 articles.

1. Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4);Choi;J. Med. Chem.,2012

2. Targeting chemokine receptor CXCR4 for treatment of HIV-1 infection, tumor progression, and metastasis;Choi;Curr. Top. Med. Chem.,2014

3. Regulation of CXCR4 signaling;Busillo;Biochim. Biophys. Acta,2007

4. CXCL12 (SDF-1)/CXCR4 pathway in cancer;Teicher;Clin. Canc. Res.,2010

5. Hematopoietic stem cells are uniquely selective in their migratory response to chemokines;Wright;J. Exp. Med.,2002

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