Discovery of Novel Bacterial RNA Polymerase Inhibitors: Pharmacophore-Based Virtual Screening and Hit Optimization-Reference-Cited by-同舟云学术

Discovery of Novel Bacterial RNA Polymerase Inhibitors: Pharmacophore-Based Virtual Screening and Hit Optimization

Published:2013-10-31 Issue:21 Volume:56 Page:8332-8338
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hinsberger Stefan¹,Hüsecken Kristina¹,Groh Matthias¹,Negri Matthias¹,Haupenthal Jörg¹,Hartmann Rolf W.¹

Affiliation:

1. Helmholtz-Institute for Pharmaceutical Research Saarland, Department of Drug Design and Optimization, and ‡Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2.3, 66123 Saarbrücken, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400485e

Reference22 articles.

1. Antibiotic Resistance: How Serious Is the Problem, and What Can Be Done?

2. The 2012 Garrod Lecture: Discovery of antibacterial drugs in the 21st century

3. Progress in targeting bacterial transcription

4. Structures of RNA polymerase–antibiotic complexes

5. Fidaxomicin: A Macrocyclic Antibiotic for the Treatment ofClostridium difficileInfection

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