Inhibition of bacterial RNA polymerase function and protein–protein interactions: a promising approach for next-generation antibacterial therapeutics-Reference-Cited by-同舟云学术

Inhibition of bacterial RNA polymerase function and protein–protein interactions: a promising approach for next-generation antibacterial therapeutics

Published:2024 Issue:5 Volume:15 Page:1471-1487
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Ye Jiqing¹²^ORCID,Kan Cheuk Hei³^ORCID,Yang Xiao³,Ma Cong¹^ORCID

Affiliation:

1. State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China

2. School of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei 230032, China

3. Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China

Abstract

The increasing prevalence of multidrug-resistant pathogens necessitates the urgent development of new antimicrobial agents with innovative modes of action for the next generation of antimicrobial therapy.

Funder

Hong Kong Polytechnic University

Chinese University of Hong Kong

Research Grants Council, University Grants Committee

Food and Health Bureau

Anhui Medical University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D3MD00690E

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3. Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects

4. Bacterial defences: mechanisms, evolution and antimicrobial resistance

5. The RNA World: molecular cooperation at the origins of life

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